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The brain changes that underlie addiction indicate a deep and entrenched history of learning, not a disease.
On a neurological level, we're beginning to have a better understanding of the brain changes that underlie the improvements in psychological well-being and reduction of mental health symptoms that have been documented with mindfulness trainings.
For example, cocaine produces long-term brain changes that underlie addiction in part by activating certain genes.
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Behavioral findings in animals and humans suggest an important role for sleep in the consolidation of learning and memory; however, much less is known about how sleep affects the synaptic and brain system-level changes that underlie these processes [1], [2].
Genetic changes that underlie specific histological subtypes are largely unknown.
Together, they initiate transcriptional changes that underlie diapause.
If so, the profile of structural and functional brain changes that can be detected in vivo during the prodromal phases of LB disease will probably also vary between DLB and PD, reflecting differences in the underlying pathology.
Repetitive Transcranial Magnetic Stimulation induces brain plasticity changes that may underlie its capacity to modulate associative memory in elders (Solé-Padullés et al., 2006).
This socially driven behavioral plasticity induces changes in brain neurogenomic states that underlie different behavioral repertoires [ 2].
We know from modern neuroscience that the brain circuits that underlie all emotions - both positive and negative - can be changed.
These changes provide structural evidence to support the concept that the core pathophysiology of PD is associated with disruptive alterations in the coordination of large-scale brain networks that underlie high-level cognition.
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