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However, accurate brain attenuation correction (AC) is required for absolute PET quantification.
A brain attenuation map was obtained using a transmission acquisition of three rod sources of 88Ge for 15 min. Then 3.7 MBq/kg of 18FDG (maximum 180 MBq) was administered intravenously, and the child remained lying in the scanner.
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In our previous study, mouse MSCs (mMSCs) were implanted into the brains of ApoE null mice, resulting in production of small amounts of ApoE in the brain and attenuation of cognitive deficits.
A μ-map of the skull was calculated from 31P-MRI and used to correct 18F-FDG PET images of the brain for skull attenuation.
Strowitzki et al. measured the attenuation of brain tissue in vivo from spectral analysis of ultrasound radiofrequency data acquired in 20 brain operations [ 11].
Further studies of the cellular correlates of attenuation characteristics in brain and brain tumors will be needed to show if attenuation curve analysis can provide a basis for detailed tissue analysis.
Fig. 1 Axial CT of the brain showing profound gaseous attenuation in the subarachnoid space, cortical sulci and ambient cistern.
The study showed that the early inhibition of HIF-1α acutely after injury provided neuroprotection after neonatal hypoxia ischemia which was associated with preservation of BBB integrity, attenuation of brain edema, and neuronal death.
Decreases in the extent of spatial activation from pre- to post-training in the majority of ROIs supported a training-related attenuation in brain activity associated with online motor learning.
In addition, attenuation of brain inflammatory response and microglial activation results in neuroprotection in various models of neurodegeneration [44] [47].
This suggests that methylphenidate's attenuation of brain reactivity to Cocaine-cues is distinct from that involved in craving.
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Justyna Jupowicz-Kozak
CEO of Professional Science Editing for Scientists @ prosciediting.com