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Subsequent studies with the same non-clinical voice-hearers have also highlighted differences in brain structure and functional connectivity (the synchronisation between different brain areas) compared with people who don't hear voices.
All sequences showed higher signal intensities of frontal and occipital brain areas compared with the temporal lobes for both WM and GM (Fig. 3).
In mice expressing PrPΔ32 93 remarkably stronger bands representing the C1 fragments were detectable in ischemic brain areas compared with C4/− sham controls as well.
We showed that the PrP in C4/− mice does not functionally rescue the Prnp−/− phenotype; furthermore it is unable to undergo β cleavage, although an increased amount of C1 fragments was found in ischemic brain areas compared with sham controls.
Structural neuroimaging studies focusing on females (Craig et al., 2007 ; Calderoni et al., 2012 ) also reveal little overlap of atypical brain areas compared with those found in meta-analyses of predominantly male samples (Radua et al., 2011 ; Via et al., 2011 ).
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Although this transmission of the MM2 subtype might be considered similar to that of VPSPr, the PrP deposition differed in form and brain area compared with the deposition observed in the VPSPr studies.
In the CeM, HAB rats showed a facilitated activation, as the number of c-Fos-positive cells was increased in this brain area compared with LAB rats (P<0.001) (Fig. 3).
There are fewer neurons in these brain areas compared to WKY [ 62- 64].
Hence, preceding activation in one brain area compared to a second brain area may reflect true causal influence or, alternatively, a hemodynamic response function that peaks earlier in time compared to the second area [ 11].
In addition, DRs were found to have significantly greater connectivity between the left TPA and all other brain areas as compared with TRs (Fig. 3 G ). Connectivity between the right TPA and other brain areas differed across brain area.
-How do the damaged areas compare with the total area of the country?
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Justyna Jupowicz-Kozak
CEO of Professional Science Editing for Scientists @ prosciediting.com