The researchers wanted to know whether the brains of people who are consistently more creative would show different activation patterns than other brains, and which brain areas would be involved.
Therefore, this differential relationship provides a natural experiment to test whether movement-associated brain areas would be adjacent to parrot vocal nuclei or instead in the same location as in songbirds, near the auditory pathway.
Although the cannulae were positioned in the VPL, further objective measurements of the spread of the JWH-133 into adjacent brain areas would be required to discount additional local sites of action.
"That area would be cordoned off.
Specifically, we anticipated that these brain areas would 1) be activated by acute hypoglycemia (AH) and 2) that this activation would be blunted after RH.
The complicated interactions between different parts of the dopamine system of the brain, and disparity between the results from the existing PET studies on ADHD, indicate that straight forward comparisons between individual brain areas would not be sufficiently sensitive to detect small abnormalities in the dopamine system.
Thus, primary areas that are connected to relatively few other cortical areas would be less variable than higher order (multimodal "association") areas, which project to and receive projections from many more disparate brain regions (Pandya et al. 1988).
It remains to be investigated whether other brain areas would reveal short-term modifications, which might be concealed by recovery in this approach.
Noteworthy, areas of the brain that would be most impacted by dysregulation in neuronal migration and proliferation that is the cerebellum, cerebral cortex, and hippocampus are also implicated in ASD [ 124, 129- 131].
It seems obvious that an imaging technique able to demonstrate areas of potentially salvageable brain would be preferable both in trials and clinical practice to the standard approach, which relies purely on clinical assessment and exclusion of intracranial haemorrhage on non-contrast CT.
