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Taking advantage of the larval zebrafish model with the transparency of its brain and the availability of genetic tools, we addressed these questions in the previous work.
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Eligibility criteria were aged 18 years and older, admitted for brain neurosurgery and the availability of krypton gas (81mKr).
Cerebral microdialysis provides essential information on brain metabolism and the availability of main energy substrates (mainly glucose) and also is potentially useful to detect secondary delayed cerebral ischemia and manage blood glucose control.
Back in the analogue era, the difference between a deep brain and a shallow brain was the availability of information and the choice of whether to take in that information or not came second.
Complications related to prolonged supportive care, as a consequence of delays in the diagnosis of brain death, reduce the availability and suitability of potentially transplantable organs [ 24, 25].
However, the normal pattern of H3K27me3 in control brain and other brain tumors is not clearly established, and the availability of a mutation-specific antibody that specifically recognizes the mutation similar to the one derived for the most common isocitrate dehydrogenase (IDH) mutation in gliomas (IDH1R132H) would greatly help clinical management [ 5].
The AMBCA is a very valuable source of connectivity data because of the consistency of the experimental methods, the standardized brain region naming, the availability of the data and the overall high level of quality of the data.
The measures necessary to increase rates of brain death, and thereby the availability of transplantable organs, would require fundamental changes in clinical care at the end of life - changes that may appear inconsistent with accepted norms surrounding what constitutes appropriate care at the end of life and the appropriate management of a good death.
Advances in neuropharmacology and neuropsychology, and the availability of brain imaging techniques have provided impetus for using drugs like psilocybin to probe the "neural underpinnings of psychotic symptom formation including ego disorders and hallucinations".
The relatively compact size of the zebrafish brain, along with the availability of a wealth of genetic, functional, and imaging tools, make it an attractive model system to explore these questions and gain insight into the cellular and molecular complexity of vertebrate brains.
Leptin regulates body weight by signaling to the brain the availability of energy stored as fat.
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