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In this study we investigated whether FT in human male subjects acts as a fetal programming mechanism on the developing brain and behavioral approach-avoidance tendencies.
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Here we present the first investigation in humans of how testosterone during fetal development predicts later neural response to valenced facial cues and individual differences in behavioral approach-avoidance tendencies.
Behavioral approach-avoidance tendencies were measured via parental report on the Sensitivity to Punishment and Sensitivity to Rewards questionnaire.
Individual differences in behavioral approach-avoidance tendencies were assessed by caregiver report on a modified version of the Sensitivity to Punishment and Sensitivity to Rewards questionnaire (50).
Behavioral approach-avoidance has not been studied so far with regard to mood, however (Trew 2011).
Furthermore, we predicted that such FT-mediated influence on neural response would predict behavioral approach-avoidance tendencies.
This suggests that behavioral approach-avoidance biases are not sensitive to mood state, but more related to depressive characteristics.
This might limit the study's generalizability, because men might exhibit different behavioral approach-avoidance tendencies than women.
We further tested whether any prior influence of FT on behavioral approach-avoidance tendencies was mediated by FT-influence on the reward system.
Her research integrates brain and behavioral approaches to understand and improve judgment, decision making, and memory across the life span.
This study applies an experimental paradigm to simultaneously investigate the relationship between PG severity and approach-avoidance behavioral tendencies.
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