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Brain activation was analyzed at whole-brain level and by a region of interest (ROI) approach.

Brain activations were analyzed in an event-related design, time-locked to the presentation of the scenario of all presented trials.

Brain activations were analyzed time-locked to recording onset, and the analyzed epoch was individually set for each trial to the duration of the respective stimulus (M = 1.75 s; range, 0.35 4.84 s).

Brain activations were analyzed time locked to recording onset, and the analyzed epoch was individually set for each trial to the duration of the respective stimulus (mean = 1.75 s; range = 0.35 – 4.84 s).

Rho activation was analyzed using Rho assay kit (Upstate Biotechnology).

We analyzed the brain responses to BART only in active mode as no brain activation was observed in passive mode, as previously reported in active versus passive mode in BART paradigm sub-section (see Fig. 9).

Brain activation was measured using a block design paradigm.

Neuromagnetic brain activation was elicited by a finger-tapping motor task.

The fMRI results revealed that their brain activation was at a level never documented before.

20 21 Ipsilateral brain activation was also observed.

Brain activation was compared within patients under either drug condition.