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As discussed previously, the doses of DPN chosen for this study were selected to bracket the dose of 1 mg/kg that we and others have used before [ 4, 33].
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However, the dose of the UB when using the International Commission on Radiological Protection (ICRP) dynamic bladder model is displayed in brackets for the human study in the "Results" and "Discussion" sections.
The two control regimens used in ICON3, which are denoted CAP 500,50,50) and carbo(6) using notation in brackets to represent the doses of individual drugs, have been shown in ICON2 to be closely equivalent (ICON Collaborators, 1998); the estimated hazard ratio for progression-free survival is 0.92 with 95% confidence interval (0.81 1.04) and for overall survival is 1.00 (0.86–1.00).
In bracket the number of cases.
In bracket the extreme of the ΔK is indicated.
The numbers in the bracket is the number of patients.
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***Values in the bracket represent the deviations of triplicate analysis.
Laboratory control samples consisting of three different dilutions of the stock solutions bracketing the expected concentrations of the dosed vaccines were also prepared and analyzed alongside the dosed vaccines on a Nippon MA-2000 mercury analyzer (Nippon Instruments Corporation).
In round brackets the number of cases.
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