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We assumed that, in general, at least 1 box of medication covers 1 month of treatment.
Randomization of the doses was pre-determined and built into the packaging, so that each numbered box of medication was dispensed in sequence to each enrolled patient.
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Patient information leaflets from boxes of medication are transformed into origami cranes, a symbol of hope.
Everyone has extra luggage allowance to accommodate several boxes of medication.
A packet of cigarettes and boxes of medication, neatly divided into daily doses, still sit on the desk where Gui Minhai would write his political gossip books on China's leaders.
"You have all types of people here," Mr. Hafizov said as he sat in the pharmacy's basement, surrounded by boxes of medication, and entered price codes into a computer database.
Spent boxes of medication were collected to assess compliance.
Each patient was given two boxes of medication during the 12-week study, each box containing 100 sachets.
To enable paramedic access to study medication and administration equipment in the prehospital setting, boxes of medication (lisinopril or placebo, identical in appearance) and other study materials (paramedic research paperwork, syringe crusher, 5 mL syringe, 5 mL vial of water) were packaged into a 'trial pack'.
We assumed a self-administered medical therapy has only 50% adherence, so at each visit, the patients were required to deliver the empty boxes of medication received, in order to improve compliance as well as to ensure the validity of the final data of the study.
The investigation started six months ago after a pharmaceutical wholesale company in Carlstadt, H.D. Smith, informed the authorities that several boxes of medications were missing from its shipments from pharmaceutical companies, Mr. Molinelli said.
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Justyna Jupowicz-Kozak
CEO of Professional Science Editing for Scientists @ prosciediting.com