Organophosphorus and carbamate compounds bind with variable affinity to the esteratic site by phosphorylation or decarbamylation, respectively, and inactivate the enzyme.
Synthetic DNA fragments at the putative promoter-binding sites bind PhoP with variable affinity, which is related to the number of mismatches in the 7 bp motifs, the positions of the mismatches, and the spacer and flanking sequences.
Nondioxin-like chemicals assume a noncoplanar configuration with chlorine atoms on the ortho benzene position and bind with variable affinities to steroid hormone receptors.
DOI: http://dx.doi.org/10.7554/eLife.02848.016 10.7554/eLiFigure48.017 Figure 5 figure supplement 2. (A ) MSI1 binds each of 7 SCD1 3′ UTR fragments containing the MSI1 consensus sequence (G/A U1 3AGU with variable affinity.
Organic cation/carnitine transporters carry carnitine with variable affinities.
We found two antibodies with only a single point mutation in the V region of their heavy chain variable domains compared to their putative germline predecessors which bound with high affinity to several Envs.
The labeled belatacept bound with high affinity to Raji cells.
The TIR1 binding pocket had the highest affinity for IAA, and although 2,4-D could bind to TIR1, it was bound with weaker affinity [64].
The peptides 60029 and 60030 bound with high affinity, whereas the peptide 60031 displayed a weak affinity (Table 1).
We previously demonstrated that SC18 HA bound with high specificity and high affinity to human receptors, while AV18 HA bound with high affinity to avian receptors.
