Sentence examples for bound with low affinity from inspiring English sources

Heparin-binding studies showed that all fragments bound with low affinity to heparin.

We previously identified the crystal structures of non-canonical peptides in complex with MHC class I (one bound with low affinity and the other with high affinity, but utilizing novel peptide anchors and MHC pockets).

The applied growth conditions in complex rich medium might not be suitable for the detection of all PdhR-DNA interactions, although the overproduction of PdhRhis should facilitate binding, also to DNA fragments which might be bound with low affinity.

Interestingly, the sequence of the binding site for Rap1 at the silencers is distinct from the genome-wide binding profile of Rap1, being a weaker match to the consensus, and indeed is bound with low affinity relative to the consensus sequence.

LacZ expressing JEG-3 cells bound to collagen I, collagen II, fibronectin, laminin and tensacin, but bound with low affinities to collagen IV and vitronectin (Figure 6A).

It is therefore likely that TGFBR1 also binds with low affinity to SB-202190 but was not detected at the threshold of 10 µM used in this study.

Instead, there are many B cells that bind with low affinity to these determinants, a binding which is insufficient for their deletion or inactivation.

The expression of CXCL4, which binds with low affinity to CXCR3, was elevated after retinal ischemia though expressed later than CXCL10.

All selectins bind with low affinity to glycans containing α2,3-linked sialic acid and α1,3-linked fucose residues such as the Sialyl Lewis x (sLex) determinant (NeuAcα2,3Galβ1,3[Fucα1,3]GlcNAcβ1-R).

SLiMs usually bind with low affinity, making them ideal for quick or transient responses, and are likely to be particularly enriched in signalling pathways (Diella et al., 2008).

Since it is known that estradiol metabolites bind with low affinity to estradiol receptors [ 37- 39] and they are less potent estrogens [ 40, 41] than the parent compound, we attempted to determine whether a weak estrogen alone or in combination with progesterone would be able to mimic the protective effect of pregnancy protection against mammary cancers.