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It is shown that HL2 forms the stable complexes with DNA only when bound with a small groove (Fig. 5a).
This problem is well-studied and algorithms exist that match the lower bound with a small gap of logd asymptotically.
The chemical compounds formed the stable complexes with DNA: HL1 when binding with a great groove and at intercalation into a small groove, while HL2 only when bound with a small groove.
At the combined action of HL1 or HL2 with C60 fullerene, the C60 + HL2 structure formed the stable complex with DNA when bound with a small groove and at intercalation into it, while the C60 + HL1 structure formed the stable complex with DNA only in one case when binding with a large groove.
It is highly protein bound with a small volume of distribution and a nine-hour half-life.
Similar(53)
This protease-inhibitor binding paradigm is observed at high resolution in a large set of crystal structures of trypsin, thrombin, and urokinase-type plasminogen activator (uPA) bound with a series of small molecule inhibitors (2- 2-phenol)indoles and 2- 2-phenol)benzimidazoles).
We just bound with a classical union bound: (19).
It is a CPU bound task with a small amount of I/O and as such is also useful for benchmarking CPUs.
In contrast, in noncultivated soil, most plutonium was bound with an organic fraction, more than 10% is permanently bound, and only a small percentage is available.
Applying the asymptotic bound with the small number of time steps resulted in some rather large bounds (≥ 1).
The 1.9 Å resolution structure of the motor domain of KSP, bound with the small molecule monastrol and Mg2+·ADP, reveals that monastrol confers inhibition by "induced-fitting" onto the protein some 12 Å away from the catalytic center of the enzyme, resulting in the creation of a previously non-existing binding pocket.
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related with a small
bound with a little
bound with a minor
bind with a small
link with a small
bound with a concrete
bound with a pleasant
bound with a large
bound with a micomolar
bound with a classical
bound with a hard
bound with a Chinese
bound with a mismatched
bound with a noiseless
bound with a weird
bound with a slow
bound with a blue
bound with a black
bound with a fine
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Justyna Jupowicz-Kozak
CEO of Professional Science Editing for Scientists @ prosciediting.com