The ligand binding cavity of PPARs is 3 4 times larger than the other nuclear receptors, indicating their capability to accommodate and bind variety of natural and synthetic lipophilic acids.
Over the next few years, we designed novel polymers containing a variety of azobenzenes bound in a variety of ways, and we elucidated some of their optical properties as a function of their structure.
Aptamers, certain kinds of DNA or RNA molecules which can bind variety of molecules at high specificity, have the overwhelming advantages over antibodies of low cost and ease of use.
Tenascin-X is an extracellular matrix protein and binds a variety of molecules in extracellular matrix and on cell membrane.
Infected erythrocytes bind a variety of host receptors but certain adhesion traits are associated with more severe disease.
Macrocyclic Lewis acidic hosts with structures incorporating electron-withdrawing icosahedral carboranes and electrophilic mercury centers bind a variety of electron-rich guests.
DFsc stoichiometrically binds a variety of divalent metal ions, including Zn II), Co II), Fe(II), and Mn II), with micromolar affinities.
Recent structural studies have revealed that riboswitches, which bind a variety of small molecule metabolites, including purine bases, S-adenosylmethionine, amino acids and cofactors, can contain sophisticated tertiary architecture that enables their function, akin to tRNA and rRNA.
EhCaBP1 is also thought to be involved in multiple pathways as it binds a variety of target proteins observed by immunoprecipitation and mass-spectrometric studies [5, unpublished observation].
COUP-TFs bind a variety of direct repeats and are thought to repress TH and RA signaling through competition for occupancy of TREs and competition for RXR, providing yet another layer of regulation [23] [25].
FERM domains bind a variety of protein and lipid ligands.
