Sentence examples for bound to two distinct from inspiring English sources
Moreover, Ubvs that bound to two distinct sites on the intracellular adapter Grb2 could be combined to generate a potent inhibitor that functioned in cells.
Among 1,732 MTLs, ≈45.9% ligands (795 entries) were bound to two distinct proteins (Figure 2E), which was lower than the result (65%) reported by Noé Sturm et al. [19].
Structural and biochemical data suggest that, at an intermediate state, Rea1 is bound to two distinct sites.
It remains to be determined if the TC C776G polymorphism has a significant effect on the hematological and neurological manifestations of B12 deficiency or on vascular and other morbidities associated with hyperhomocysteinemia. Vitamin B12 (B12) in plasma is bound to two distinct transport proteins, haptocorrin and transcobalamin (TC) (Chanarin, 1969; Green and Miller, 2007).
The ET family consists of three isopeptides, ET-1, ET-2, and ET-3, which bind to two distinct subtypes, ETAR and ETBR, of G protein-coupled receptors [20].
The endothelin system consists of three peptide ligands (ET-1, ET-2, and ET-3), which bind to two distinct G protein-coupled receptors designated ETA and ETB [ 4].
DKK-1 and Wnt ligands bind to two distinct recognition sites on the LRP 5/6 coreceptors, indicating that antagonists of DKK-1 might interfere with the interaction between DKK-1 and LRP 5/6 without affecting Wnt binding to the receptors [ 63].
They bind to three distinct epitopes: epitope I (1a2y and 1jhl), epitope II (1p2c and 2iff) and epitope III (1j1x) (see Supplementary Section 5).
This is further supported by our modeling studies, showing that NeoR6 and CXCL12 bind to two distinct sites on CXCR4, in contrast with other CXCR4 inhibitors, e.g. T140 and AMD3100.
