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The surface atoms on the perfect polar faces are tightly bound to three adjacent atoms in the bulk material, while the atoms in the underlying layer are only bound to one atom in the bulk.
Given the short distance (6 bonds excluding side-arms of K-residues) between two RGD motifs in E[c RGDfK ]2 and E[c RGDyK ]2, it is unlikely that they would bind to two adjacent αvβ3 sites simultaneously.
Both Ikaros and Aiolos can bind to two adjacent Ik1 and Ik2 sites proximal to the λ5 transcription start site.
Binding of a single EPO molecule to two adjacent EPO receptors on the membrane of target cells leads to homodimerization of the receptors and the triggering of different intracellular signaling pathways that might play an as yet unidentified role in cellular protection from stress.
It might be that these domains are orientated such that they are able to simultaneously bind to both the phosphorylated serine and the phosphorylated threonine of a single SDTD motif, or to two adjacent SDTD motifs in the MDC1 protein.
It thus converts adjacent PPDK1- PPDK2 subunits either to two adjacent PPDK1 subunits, or two adjacent PPDK2 subunits.
In silico analysis of HDAC6 SMAR1 Ku70 docked model revealed that Ku70 is bound to SMAR1 adjacent to HDAC6-binding site.
As transcriptional activator, reduced OxyR binds to two pairs of adjacent major grooves separated by one helical turn of the DNA duplex and acts to repress its own synthesis.
Stay bound to adjacent players until the ruck is finished.
The ratio of two types N indicates that they are mainly bonded to three adjacent carbons, suggesting that the N atoms are uniformly bound to the graphene structure.
This bound PrP1 could then dephosphorylate both NKCC1 itself, and SPAK/OSR1 bound to NKCC1 at an adjacent site [35].
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Justyna Jupowicz-Kozak
CEO of Professional Science Editing for Scientists @ prosciediting.com