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Therefore anchoring at the N-terminus of 10FNIII (Val in Figure 1B) models the scenario where the upstream FN modules are tightly bound to these components and therefore remains relatively stationary, while cellular forces are applied at the RGD loop.
As additives they are not chemically bound to these components and over time they migrate out.
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While PEI-GNRs directly interacted with B16 cell membranes, BSA-GNRs were always bound to the components of cell detritus.
Bone is comprised of 95% collagen type I, with fibronectin and laminin present within the bone marrow ECM (Vituri et al, 2000) and laminin also a key component of the sinusoidal basement membrane (Gu et al, 2003), so the upregulation of integrins that bind to these ECM components may explain the fact that breast cancer cells predominately metastasise to bone (Powell et al, 1991).
If sugar molecules are added incorrectly, dystroglycan loses its ability to bind to these components.
It is strongly bound to landscape components and features and to their spatial and functional interrelations.
Growth factors bound to ECM components can be released by MMPs (Hawinkels et al. 2008).
Two components are presumably bound to cell-wall components, i.e. the CscA is membrane-anchored and CscD is bound to peptidoglycan.
Therefore, the DcPES1 protein appears to be a component of or tightly bound to components of the nuclear matrix.
We found that TERRAs directly bound to the PRC2 components EZH2 and SUZ12.
We demonstrated that both endogenous and exogenous dysbindin-1 bound to components of DNA-PK, Ku70, and Ku80 in neuronal cells by immunoprecipitation, immunocytochemical staining, and subcellular fractionation.
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