Sentence examples for bound to the operator from inspiring English sources
Transcription of the fructose operon is repressed when Cra is bound to the operator, which is located on the downstream region of the RNA polymerase binding site [ 24].
One of its striking features is that even if the repressor (TetR2 protein) is bound to the operator tetO2, RNAp can still be recruited to the promoter tetP R 2 and start transcription if tetO1 is free [ 32].
The results of analytical ultracentrifugation demonstrate that TtgR forms stable dimers in solution, and that two dimers bind to the operator.
In the monomeric pathway monomers bind to the operator site and then recruit another monomer to form a dimer directly on the DNA.
The tetR gene encodes TetR which binds to the operators, acts as a repressor and inhibits the expression of both genes in the absence of Tc.
This phenomenon is expected since the Lac repressor exists always as tetramers under the conditions used here [47], [48], and competition for binding at the second operator between loose Lac repressor and Lac repressor bound to the other operator is stronger as the concentration of Lac repressor increases.
For example, suppose that a repressor tetramer is bound to
However, an MS2 coat protein-mRNA export factor fusion, when bound to the MS2 operators, overcomes nuclear retention, leading to export of the pre-mRNA and luciferase expression.
Expression of this operon is induced by the presence of camphor, because a TetR-homolog transcription factor, CamR, dissociates from the bound operator when bound to the camphor ligand.
At intermediate concentrations, the equilibrium will be dominated by states in which a single repressor tetramer is bound to the DNA at the strong operator, punctuated by transient looping events.
