Sentence examples for bound to the open from inspiring English sources

By weakening interactions of the N-subdomain believed to stabilize the closed complex, an intermediate complex with an incoming nucleotide bound to the open conformation was determined.

Thus, just like the competition experiments of AIP and CARMA1 GUK for CARMA1 PDZ-SH3, the endogenous association studies suggest that AIP is predominantly bound to the open and active CARMA1 conformation within the CBM complex.

Two ligands (ACD and AOB) are bound to the open form of FABP4, and the other two (ANS and TGZ) are bound with the closed form in the crystal structures.

So at MariaDB, the team decided to now license the latest version of its MaxScale database proxy under the BSL (MariaDB itself is a fork of MySQL, so it is forever bound to the open-source GPL license that MySQL is licensed under).

The results suggest that the agent preferentially binds to the open state of the K+ channel [30], [31].

All of the active compounds bind to the open-inactivated states of the channels and therefore act as state-dependent modulators.

Therefore, even though efficient processing of hairpin coding ends requires DNA-PKCS, this may occur by activation of the kinase bound to the cogenerated open signal end rather than to the hairpin end itself.

The Getaway, quite often a bad game, and itself sadly bound to the idea that open worlds should be playgrounds for driving and shooting, is not a wholesale rebuttal to the kinds of sandbox games that exist today, but it could have been should have been the nexus point for a different strain of open-world design.

The Getaway, quite often a bad game, and itself sadly bound to the idea that open worlds should be playgrounds for driving and shooting, is not a wholesale rebuttal to the kinds of sandbox games that exist today, but it could have been – should have been – the nexus point for a different strain of open-world design.

Overlay of the structures of active, phosphorylated AMP-bound holo-AMPK with that of the inactive KD-AID fragment clearly shows two alternative AID conformations: the AID with helix α3 either bound to the KD in the inactive, open conformation or being released from the inhibitory KD interaction and bound to the γ-subunit.

AP-2 can transition between metastable states; a partially open form bound to the dileucine sorting signal has been characterized (Kelly et al., 2008).