Thus, both amino- and carboxy-termini appear to influence the migration and, putatively, the structure of BORIS-DNA complexes, which may lead to different functions of BORIS isoforms bound to the same target.To evaluate the effect of DNA methylation on the binding activities of BORIS isoforms, we performed EMSAs using a H19 ICR probe with CpGs methylated in vitro by SssI methyltransferase.
Deformation energy, which defines the energy required to bend DNA from its native shape to its shape when bound to the ZFP, is an effect of indirect recognition mechanism.
A memory effect, bound to the pre-hardening gradient, was introduced into an elasto visco-plastic modelasto visco-plasticmodelthe stress and strain fields at the inner surface.
In contrast, we observed that locostatin, which also bound to the RKIP pocket, had no effect on RKIP-Raf-1 interaction [27]; we have attributed locostatin's inability to perturb RKIP function to its smaller size than DHPE.
However, it is believed to be important for the CpG to be bound to the Alum to elicit its effect.
The music is so bound to the libretto, visuals, choreography and special effects that it is impossible to assess the quality of Mr. Wallace's score on its own.
When 1.5 millimolars of meth was introduced into the influx BBB chip, about 10% of the dose crossed the barrier, entered the brain chip, and bound to the neurons, mimicking the real neurological effects of the drug.
This rules out member-specific occupancy of NFI sites as an explanation for the ko phenotype, and strongly favors the hypothesis that different members of the NFI proteins have different regulatory effects when bound to the same cis-regulatory DNA element.
Pb is not only bound to the erythrocytes, but also has direct effects on erythropoiesis, which can lead to anemia.
Research staff and research commissioning by departments and agencies are bound to feel the effects of the substantial reductions in 'administration' announced by the Treasury.
