Sentence examples for bound to the bone from inspiring English sources

The results presented here overlap somewhat with earlier studies done to identify the proteins bound to the bone mineral.

In our study the amount of bisphosphonate bound to the bone mineral seemed to be more important than unbound.

Once chemically bound to the bone in the fracture gap, bisphosphonates remain for a long time until resorbed.

The remainder of the dose is presumed to be bound to the bone, where it is slowly released over time, resulting in low plasma levels [ 23, 24].

Sm-EDTMP was bound to the bone in a stable manner because the decrease in uptake between 6 and 48 h was due solely to the physical decay of Sm.

The metacarpal bases are bound to the bones of wrist by tough ligaments, but further out, towards the fingers themselves, they are held fairly loosely.

The most commonly used class of osteoclast inhibitors includes bisphosphonates, which bind to the bone promoting osteoclast apoptosis and inhibiting osteoclast mediated bone resorption [ 38].

This is probably due to the fact that serum concentrations of ZA are very low, as ZA immediately binds to the bone matrix after injection.

The osteoclast precursor arises principally in the marrow as an early mononuclear macrophage; it circulates and binds to the bone surface [ 8].

Microcracks tend to accumulate in old bone that is unlikely to contain bisphosphonate, because bisphosphonates bind to the bone surface, and the old bone was formed and embedded before treatment started.

Over time, the micelles could extravasate from the bloodstream as they bind to the bone at the tumor site and eventually the blood concentration would dip below the critical micelle concentration; micelles then destabilize into unimers, which are readily cleared as is the covalently bound DOX.