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After absorption, vitamin D is bound to the binding protein and carried to the liver via the bloodstream.
β-mannose on the lipoplexes shields the cationic characteristic of DOTAP and prevents nonspecific binding, whereas α-mannose not only exhibited the same effect as β-mannose but also was definitely recognized and bound to the binding site.
In terms of these variables various tissue characteristics can be calculated for the different tissue compartments, e.g., the total amount of VEGF165 bound to the binding sites of the ECM is equal to U AV, ECM × [ V165 M ECM ] AV, where [ V165 M ECM ] AV is the concentration of VEGF165 bound to the ECM in moles per liter of available ECM fluid volume.
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The results showed that all of these compounds bind to the binding site of BCRP with relatively suitable binding energies and therefore could be potential inhibitors of both αβ-tubulin and BCRP proteins.
The compounds strongly bound to the hydrophobic binding pocket of a-FABP, while showed significantly lower binding affinities to the closely related homologue protein h-FABP.
Description: Structure of tellurium-centred Anderson-Evans polyoxotungstate (TEW) bound to the nucleotide binding domain of HSP70.
Ahmed AH, Hamada M, Shinada T, Ohfune Y, Weerasinghe L, Garner PP, Oswald RE, "The structure of -kaitocephalin bound to the ligand binding domain of the AMPA/glutamate receptor, GluA2," J. Biol.
We have determined the crystal structure of human leukemia inhibitory factor (LIF) bound to the cytokine binding region (CHR) of gp130 at 2.5 A resolution.
Furthermore, the inhibitor of IN-LEDGF/p75 interaction was properly bound to the LEDGF/p75 binding site on IN.
In our structure, sulfate ions are bound to the canonical binding site, but not to the proposed secondary site.
Small-angle X-ray scattering measurements of human haptoglobin haemoglobin bound to the ligand-binding fragment of CD163 confirm receptor binding in this area, and show that the rigid dimeric complex can bind two receptors.
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