Sentence examples for bound to the activation from inspiring English sources

A recent cryo-electron microscopy (EM) analysis revealed that pol II adopted a stable orientation within a Mediator pol II TFIIF assembly in which Mediator was bound to the activation domain of viral protein 16 (VP16).

C4d remains covalently bound to the activation point.

Since peptides bound to the activation segment and the SH2 domain should be in the same N- to C-terminal orientation, the Fes phosphorylation site and the pTyr that recognize the Fes SH2 domain could, in principle, be connected within the same polypeptide chain by a short intervening sequence (see Figure 7).

NMR solution structures of KIX bound to the activation domain of the transcription factor c-Myb indicate that the positions that are equivalent to I137 and L141 in pKID are taken by two leucine residues in c-Myb (L298 and L302, both part of the c-Myb ΦXXΦΦ motif).

Coactivators bind to the activation function-2 domain of TR, which is located at the C-terminus of the LBD.

AATYK1A bound to the p35 activation subunit of Cdk5 in cultured cells and in mouse brains and colocalized with p35 on endosomes in COS-7 cells.

Nanomolar gamma blocks the activation of PDE by micromolar T alpha-GTP gamma S. The degree of activation of PDE depends reciprocally on the concentrations of gamma and T alpha-GTP gamma S. gamma remains bound to the disk membrane during the activation of PDE by transducin.

Presently available evidence suggests that once AdA or IP3 has bound to the IBC, each causes indistinguishable activation of the IP3R (Rossi et al., 2009).

The protein content of α-granules includes soluble proteins that are secreted to promote coagulation as well as proteins that are bound to the external platelet surface during activation.

Indeed, the Hsp70 protein is a negative regulator of mitochondrial pathway of apoptosis, as it binds to the caspase activation and recruitment domain (CARD) of apoptotic protease-activating factor-1 (Apaf-1), preventing apoptosome complex formation.

It directly binds to the C-terminal activation domain of β-catenin and inhibits β-catenin-mediated transcriptional activation [20], [21], [22].