Sentence examples for bound to small molecules from inspiring English sources
In general, the conformation of HSA will change when it is bound to small molecules.
In the aqueous-phase extract of D. radiodurans homogenate, which was used to prepare DR-ultrafiltrate, Mn was bound to small molecules (<3 kDa), which included peptides (Figure 2D).
Riboswitches are mRNA elements that change conformation when bound to small molecules.
The whole Protein Data Bank was then searched using an advanced query for free protein structures corresponding to each complex bound to small molecule inhibitors (supplementary material, Fig. S3).
For example, the light-sensing region of a photoreceptor typically binds to small molecules called chromophores that are able to absorb light.
It is interesting to note that orphan NRs bind to small molecules with lower affinity (Kd values in µM range) unlike endocrine NRs that display high-affinity binding (Kd values in nM range) (5, 9).
Located in the 5′ untranslated regions (UTRs) of mRNA, riboswitches directly bind to small molecule metabolites through their aptamer domain, triggering a conformational change that alters expression of the downstream gene.
When this finding is combined with the results already discussed, the picture that emerges is that within the PII trimer, the subunit binding the receptor must be bound by the small molecule effectors, and the other subunits of the trimer can influence its activity by intersubunit signaling when they bind to small molecule effectors.
Mups are lipocalins that function as pheromones, either alone or when bound to small hydrophobic molecules [ 68, 69] and are important in reproductive cycle of rodents where urine-derived signals control sexual attraction, mating and puberty onset [ 70- 73].
