The environment can serve as a long-term reservoir of CWD and scrapie infectivity [34], [35] and prions bound to soil retain infectivity [9], [13], [23], but it remains unclear whether soil-bound prions play a significant role in indirect CWD and/or scrapie transmission.
Immunoglobulins bound to collagen retain their ability to form antigen antibody complexes, which may become deposited on the vessels.
In contrast, Z α1-antitrypsin bound to mAb4B12 retained almost two thirds of its inhibitory activity against neutrophil elastase in vitro, supporting the use of mAb4B12 (as whole antibody or intrabody) as a research tool in α1-antitrypsin deficiency.
Atomic force microscopy studies indicated that alkyl chains bind to and retain segregated interfacial surfactant phases at low surface tensions by inducing 3D structural transitions in the monolayer's fluid-like phase, forming surfactant-associated reservoirs.
The resultant scFv (B6-1) bound to αvβ6 but retained residual reactivity with CEA.
MBP SepF mutant fusions, bound to amylose resin, retained significantly less FtsZ compared with wild-type protein.
There is an age-related loss of the G3 domain of PG, and 92% of the G3 domain is lost as part of the normal turnover of the PGs, whereas the rest of the molecule bound to HA is retained in the cartilage [ 99].
As described above, in the process of aging, the vast majority of the G3 domain is lost as the part of the normal turnover of cartilage PG aggrecan [ 99], whereas the rest of the molecule, including the G1 domain which is bound to hyaluronan, is retained in the cartilage.
TECs bound to the hydrogel composites retained their molecular properties; and when transplanted into athymic nude mice, they supported the development of functional T-cells.
