Identifying the orientation of XPD bound to DNA is a prerequisite for establishing how directional translocation is determined in SF2 helicases.
The formation of DNA adducts (i.e., carcinogens covalently bound to DNA) is widely considered a prerequisite for the initiation and progression of cancer development.
At a time when freedom and democracy were entering the ideological lexicons around the world, Existentialism, with its abstract conception of freedom bound to recognized responsibility, heralded free will as a basic prerequisite of human existence.
Dimerization is consequently a prerequisite to DNA binding and, when not bound to DNA, the dimers readily dissociate back to monomers [ 3].
The integrity of viral capsid structure, including antigenic sites, is prerequisite to maintain infectivity, and viral particles bound to specific antibodies might be structurally intact.
As the target of both types of T cells is a peptide bound to an MHC molecule, binding to MHC is a necessary prerequisite for a peptide to induce a T-cell response.
The English major is vanishing from our colleges as the Latin prerequisite vanished before it, we're told, a dying choice bound to a dead subject.
A prerequisite for a successful layout generation process is that all ligands are bound to the same active site and protein chain; otherwise no common residues can be found by the algorithm and the layout alignment fails.
Such small polities would be bound to come into frequent conflict, and much of our time would be spent fighting or preparing to fight; military service would be a prerequisite for political eligibility.
