Sentence examples for bound to guide from inspiring English sources

Liu et al.[10] deduce a boosting error bound to guide the tracker construction and semi-supervised learning in Adaboost framework.

Nevertheless, the recent solution of the crystal structure of the Cas9 protein bound to guide RNA and substrate DNA showing the mode of interaction between the PAM site and the Cas9 protein will hopefully facilitate directed evolution studies to re-engineer the PAM sequence requirement or even to completely remove the PAM dependency [ 87, 88].

These proteins are involved in RNA editing and bind to guide RNAs (gRNAs) that specify where uracil residues are added or removed in the sequence of the mitochondrial pre-mRNA [ 35].

(B ) Crystal structure of Ago2 bound to a guide RNA (red) and target RNA bearing t1A nucleotide (blue; PDB ID: 4W5O).

We recently reported crystal structures of human Argonaute2 (Ago2) bound to a guide RNA and short, seed-paired target RNAs (Schirle et al., 2014).

Recent crystal structures of Ago bound to a guide strand and its target RNA further highlighted the significance of the A-form helix in RISC catalysis.

Since the A. fulgidus templates represent better resolution structures, the final illustrated Ago2 models are based on the mid domain from A. fulgidus Piwi alone [PDB: 1w9h] and bound to double-stranded guide [PDB: 2bgg].

To regulate target mRNAs mature miRNAs are bound to AGO proteins and guide the AGO-associated RNA induced silencing complex (RISC) to mRNA targets through imperfect base pairing between the miRNA and the target.

Inequality is bound to grow when the guiding principle for sharing out resources shifts from entitlement to competition.

They are designed such that the drug or ligand is bound to its surface and guided with an external magnetic field to the desired site.

In addition to the three conserved domains, both pAgos whose structures have been solved contain an N-terminal domain, an L1 domain, and a PAZ domain that, as in eukaryotic Argonaute, binds the 3' end of a siRNA guide and positions the middle of siRNA guide bound to the target mRNA in the catalytic pocket of the PIWI nuclease [ 32- 34].