Sentence examples for bound to a putative from inspiring English sources

Potentially related is the observation that S1P bound to a putative TRPC3-PLCγ1 intermolecular domain that also interacted with PI phosphates, although the functional relevance of this binding was not determined (van Rossum et al. 2005).

dRFX was identified through a homology search for the RFX DNA binding domain (DBD) and dRFX2 was identified through yeast-one-hybrid (Y1H) screening for transcription factors that bind to a putative promoter sequence [ 13, 14].

A recent crystal structure of the Ffh protein bound to a signal sequence revealed a putative induced-fit mechanism that leads to accommodation of the signal sequence within the hydrophobic groove of the SRP protein [ 68].

The PLU-1/JARID1B ARID domain preferentially binds to a GCACA motif, a putative consensus sequence that is abundant in MT promoters.

Using highly purified polysaccharides, we were able to show that opsonic antibodies are directed against only two of these antigens: In acapsular strains, LTA is the major opsonic epitope and in encapsulated strains opsonic antibodies bind to a novel diheteroglycan, the putative capsular polysaccharide of E. faecalis in CPS-C and CPS-D strains.

A de novo drug design methodology was used to generate an initial set of structures that could potentially bind to a putative binding site.

The ability of ZNF9 to bind to a putative IRES element in the absence of other proteins suggests that it may act as an ITAF through direct recognition of the IRES sequence.

In adipocytes, STAT5A binds to a putative STAT site in the PDK4 promoter in response to PRL stimulation [ 35].

SREBP1 has been shown to bind to a putative E-box motif at -1535 bp of the PPARγ1 promoter, and mutation of this motif inhibits SREBP1 binding [ 66].

Chromatin immunoprecipitation assay further revealed that ER α could bind to a putative estrogen response element region of the INPP4B promoter in bladder cancer cells.

We then evaluated in MCF7 3-D spheroids and in MCF7 hypoxic cells whether HIF-1α may bind to a putative HRE within the promoter region of the MDR-1 gene, increasing Pgp transcription, by a ChIP assay.