Your English writing platform
Discover LudwigExact(18)
These interactions appear to contribute to the slower HDX in the ligand bound structures.
The disordered L2 region of the "free" protein has a well-defined conformation in the RNA bound structures.
In both cases the proteins were crystallized in absence of RNA for future comparison with RNA bound structures.
The last two columns of Table 1 give the pdb codes of the ligand free and ligand bound structures.
As in p1-p6 bound structures, the representative members of the second largest clusters are also investigated by ANM.
Moreover, use of X-ray crystallography to solve numerous drug or ligand bound structures can be laborious or not feasible.
Similar(42)
The nucleoside-bound structures of vcCNT help to shed light upon the structural basis of the importance of this residue.
Many aquatic bacteria produce gas vacuoles, which are protein-bound structures that contain air and allow the bacteria to adjust their buoyancy.
The inhibitor-bound structures reveal two distinct binding sites in the CNOT7-binding interface of Tob (Fig. 2A and 2B).
This necessitates using predicted ligand binding sites, which are often less accurate than those extracted from ligand-bound structures.
In the same way, two agonist-bound structures were available for SF1 but no selective pharmacophore could be obtained.
Write better and faster with AI suggestions while staying true to your unique style.
Since I tried Ludwig back in 2017, I have been constantly using it in both editing and translation. Ever since, I suggest it to my translators at ProSciEditing.

Justyna Jupowicz-Kozak
CEO of Professional Science Editing for Scientists @ prosciediting.com