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The C-terminus can undergo large conformational changes between a closed, ligand-bound structure, and an open, membrane bound structure that enables phospholipid binding and release [ 20].
(A) Superposition of the Mg-ADP bound structure (colored) and the ATP + GBM bound structure (gray) by aligning the TMD0 domain of SUR1.
The membrane bound structure of AY1 reveals a "helical hairpin" (helix-loop-helix) structure22,23.
(e) Close-up of bottom view of the N144 in the Na+ bound structure of SaTRIC (type 2a).
He uses the natural grab and snagging properties of the branches to thread and weave them into a tightly bound structure.
Stars can form part of a much larger gravitationally bound structure, such as a star cluster or a galaxy.
Similar(42)
The zinc-bound structure has two metal ions bound in the active site in all protomers.
"We did a lot of studies to figure out how drugs bind to it and what's the drug-bound structure," Hong says.
The PTX-bound structure is shown in grey and the ALP/GABA-bound structure is coloured by subunit (α1, red; β3, blue; γ2, yellow).
The bosentan-bound structure was determined by molecular replacement, using the K-8794-bound K-8794-bound K-8794-boundly rebuilt and refined astructureed andve.
The PTX-bound structure is shown in grey and the BCC-bound structure is coloured by subunit (α1, red; β3, blue; γ2, yellow).
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Justyna Jupowicz-Kozak
CEO of Professional Science Editing for Scientists @ prosciediting.com