Sentence examples for bound segment from inspiring English sources
In a first attempt to identify genes that may be regulated by HSF binding, we identified the nearest transcription start site (TSS) to the peak of each HSF bound segment.
During refinement non-crystallographic restraints were added to the DYNLL2 molecules of the dimer as well as to the bound segment and coiled coil region of the engineered peptide.
Thus, for each HSF bound segment we assigned a "peak" as the center of probe in the segment with the lowest P[Xbar] (i.e. the probe with the lowest probability that the observed difference between ChIP and WCE signals is due to non-biological causes).
The simplest explanation for this effect is that bridging requires the interaction of an H-NS-free DNA segment with an H-NS bound segment to nucleate formation of a 2-duplex bridged structure such as that proposed by Arold et al. (2010).
If we look at our top 100 HSF bound segments, 90 were also identified as HSF binding sites by this group.
The HSF bound segments identified in our analysis span several oligonuclotide probes from the tiling array and average 1400 bp in length.
For example, even though each system resulted in more than 200 differentially expressed transcripts, only 33 or about 8% of these transcripts were in common to both systems and of these genes, only 9 had HSF bound segments within 1250 bp of a TSS.
Every ChIP-Seq dataset is a mixture of directly bound segments and regions that may reflect alternative influences.
In this assay, chromatin bound CgrA was cross-linked to its target site in vivo, the DNA was then isolated, sheared, depleted of non-specific protein and nucleic acids by immunoprecipitation of CgrA bound segments, de-crosslinked from CgrA and then sequenced by high-throughput DNA sequencing.
Exhaust e emission upper bound on segment q. Unit fuel cost.
The bound SRGTQTE segment of the peptide preserves the 5 backbone hydrogen bonds of the β-sheet interaction and the 11 additional hydrogen bonds of the high resolution complex structure (Figure 4F).
