Sentence examples for bound pathway from inspiring English sources

The cell death program may be activated via a membrane bound pathway, where the signal is initiated by so called 'death receptors' [ 12] or via the mitochondrion [ 13].

The precisely tuned gene activity underlying such circuits is in the purview of transcription factors that may bind pathway intermediates, which in turn modulate transcription factor function and therefore gene expression.

The SoxXA complex then covalently binds other pathway intermediates to the SoxY cysteine thus forming extended chains of sulfane (S−) groups preceding the terminal sulfone group (SO3−) [182].

Another pathway bound by RXRα/PPARα is the acylglycerol metabolic process, which is involved in triglyceride homeostasis.

Furin-like convertases can be localized to the TGN, within granules of the regulated secretory pathway, bound to the cell surface or potentially in the extracellular matrix [ 15].

In these studies, we first aimed to understand how three different products were formed over the course of the reaction, though the crystal structure of 1,6-DHN bound suggested a pathway for only one product (5-geranyl-1,6-DHN).

These findings indicate that PR signals to moesin via a G protein-dependent pathway when bound by P, and via a PI3K-dependent pathway in the presence of MPA.

A curation project involving, e.g. a heavily studied pathway such as the Wnt signaling pathway is bound to be based on a set of prioritized information (53) rather than on an exhaustive analysis.

In addition, an in vitro study demonstrated that significantly more C4b-binding protein (C4BP) (the classical pathway inhibitor) and factor H (FH) (the alternative pathway inhibitor) bound to the transparent strain compared with the opaque one.

While the second K+ ion reached the lower binding site between the bottom and central G-tetrads through the bottom pathway, it bound at 159.3 ns and spent about 5.6 ns to accomplish the binding process.

A number of these, including Grb2 and ShcA, are from proteins predicted to promote downstream activation of the RAS/MAPK pathway when bound to activated RTKs.