Single-purpose smart devices like this one are bound to be niche products, but with enough interest (the basketball market is huge) and potential professional adoption, this could be the next big trend in wearables.
For example, when Chlamydia trachomatis invades a mammalian cell, a membrane-bound niche called an inclusion is established, and the host Golgi is fragmented so that the remnant Golgi membrane can be aligned around the inclusion (Heuer et al., 2009).
Now, I'm sure the studios have reams of research and focus-group testing to show why "The Hurt Locker" was bound to be a niche film at best.
A parabiosis study, in which the circulatory systems of young and old mice were bound, demonstrated that the microenvironment or niche mediate the age-related dysfunction in myogenic progenitors (Conboy et al., 2005).
Since the neurogenic niche in the SGZ is bound by the vasculature (Palmer et al., 2000), we used a Pecam-1/CD31 antibody to identify blood vessels.
Combined, these experiments revealed that the quiescent niche consists of axonal, membrane bound, Nrg1-3 that signals to ErbB receptors within Schwann cells.
Since both inhibitors bind within the proximal niche, the formation of an ESI complex implicates substrate binding within the distal niche near the iron sulfur protein (ISP) and cytochrome c1 (c1).
Battery life is bound to improve, but until then, the Watch is likely to remain a niche product in the domain of Apple enthusiasts.
The presence of CXCR4 on the cell surface bound to other factors promotes migration and homing into or from the BM niche [ 23, 24].
As in almost any sector, you are bound to be faced with competition so you need to carve out a niche for yourself to establish a reputation and gradually build a customer base.
Which metals are actually bound and efficiently transported in vivo will likely also depend on metal bioavailability in the niche being colonized.
