The results are summarized in Table 2 and showed that Stx bound mostly to monocytes and platelets, particularly after activation, and that minimal binding to platelet-free neutrophils was detected.
During hyphal induction, Tpk2 bound mostly to promoter regions of genes involved in filamentous growth (40 genes including HGC1, RAS1).
They found that in the nucleus the NOVA proteins bind primarily to intronic regions of the RNA transcript: however, in the cytoplasm they bind mostly to 3′ untranslated regions of the transcripts.
miRNAs bind mostly to mRNA segments originating from the 3' UTRs of genes [ 6], but the mechanism of translational repression is only partially understood.
Altogether our results demonstrate that MSL and NSL bind mostly to distinct sites in mESCs.
Induced GATA1 binds mostly to regions primed by GATA2 in MPCs and bound by both GATA2 and GATA1 in E5 cells.
While Tat is known to bind mostly to the surface of CycT1 (Schulze-Gahmen et al., 2014), the PID appears to contact both CycT1 and CDK9 (Yang et al., 2005; Itzen et al., 2014).
They are composed of 18 23 nucleotides and bind mostly to target sequences within the 3′ UTR or in rare cases to the coding region of their target mRNAs thereby inhibiting protein expression.
The Sambucus nigra agglutinin (SNA) directed against glycans with the terminal α2,6-linked sialic acid has been shown to bind mostly to Fab glycans that, in contrast to Fc glycans, are fully sialylated and strongly SNA reactive [ 25– 28].
Tudor domains of JMJD2A bind mostly to trimethylated H3K4, trimethylated H3K9 and di,trimethylated H4K20 [14].
