The structure with a covalently bound mechanism-based inhibitor is similar to, but not identical with, the design model, with an RMSD of 1.4 Å over active-site residues and equivalent substrate atoms.
Binding mechanisms of treated and non-treated clays are different.
Binding mechanisms were studied using Molecular docking method.
Binding mechanism indicated that small hydrophobic substituents attached to the arylpiperazine moiety were essential for rational design of α1D-selective antagonists.
Having internalised these double bind-mechanisms perfectly after a while under the double bind-regime, the employees become so intimidated that they will do whatever they are told without contradiction or question regardless of any hint of the real dangers for the organisation.
Binding mechanism and properties of alkali-activated fly ash/slag (AAFS) mortars with various ratios of fly ash to slag were investigated by compressive strength test, flexural strength test, water absorption test, drying shrinkage test, scanning electron microscopy (SEM) and X-ray diffraction (XRD) analysis.
It is now clear that stress and the ageing process share a number of underlying mechanisms bound in a very close, if not indissociable, relationship.
The first paper presented in this special issue, is especially devoted to the above-listed key trend (1) of open learning, focusing on massive open online courses (MOOCs) that allow more people to gain access to education, regardless of their learning background and where content delivery is not anymore bound on standard mechanisms and physical attendance of lectures.
Directed migration is based on gradients of attractive or repulsive molecular cues that are either diffusible or surface bound., Guidance mechanisms share some characteristic hallmarks that distinguish them from tissue patterns generated by random processes.
He saw that the very nature of casual cinematic recording, apart from the studio-bound mechanisms of the commercial cinema, would bring about a new form of moviemaking, in which the material and practical situation of the filmmaker, including the discovery of his stories and characters, would be an essential part of the resulting film.
