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It is possible that this clone recognizes a different binding surface of the PSP94 in comparison to the other binders and that this membrane PSP94, bound in an oriented way to its cognate cell-surface receptor, is sterically hindered and, thus, partially unapproachable for a full PAB036 recognition.
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Five arrows tightly bound in a sheath.
For efficient cleavage, EcoP15I normally requires the interaction of two enzyme complexes that bind to sites oriented in a head-to-head fashion.
In this section, we will give an application of the previous results - to obtain a sharp upper bound of the skew-spectral radius of an oriented unicyclic graph.
Finally, in Section 4, we give an application of the previous results - to obtain a sharp upper bound of the skew-spectral radius of an oriented unicyclic graph.
Merotelically attached kinetochores were then identified by scrolling through the Z-axis to visualize kinetochores bound to microtubule bundles oriented in opposite directions.
Binding of these peptides to GRP78 was confirmed using an oriented immobilization technique for the Biacore system.
Both substrates were unable to bind in a proper orientation in the active site pocket and this could be due to the differently oriented side chains.
The first involves a rapid equilibrium between the type II bound substrate and a metabolically oriented binding mode.
The TTR∶DDBF co-crystal structure showed that the tricyclic ring of DDBF effectively utilizes the hydrophobicity of the outer binding pocket and binds in a forward binding mode, orienting its directly linked carboxyl moiety towards Lys15.
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