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However, no upper bound has been established so far for this logic.
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It has been established that miRNAs bind to mRNAs predominantly in 3′-untranslated regions (3′ UTRs) [ 2].
In a similar analogy, in the mycobacterial CoaE, conformational changes induced upon DCoA binding (which as has been established previously, binds first), could in all probability, bring Arg140 closer to the ATP phosphate groups.
It has been established that COP I binds directly to proteins bearing the di-lysine motif.
Both the Rad51 N-terminal and RecA C-terminal domains have been shown to bind DNA, but no role for these domains has been established.
While it has been established that PrP is competent to bind nucleic acid, it is also known to bind many other ligands including polyanionic glycosaminoglycans ('GAGs').
It has been established that majority of circulating vitamin D is bound both to vitamin D binding protein and albumin [ 50, 51].
In contrast to TRα1 and TRβ, it has been established that TRα2 does not bind T3 (15, 41).
To enrich a class of mRNAs directly bound to the RISC complex, the method designated as ribonucleoprotein immunoprecipitation (IP) followed by GeneChip (RIP-Chip) has been established.
Many of these proteins have been shown to bind DNA, but no clear sequence or structural relationship to known DNA binding motifs has been established.
This has been established.
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Justyna Jupowicz-Kozak
CEO of Professional Science Editing for Scientists @ prosciediting.com