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The bound cells can be released after the re-invasion and collected for continuous culture.
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More broadly, it is likely that the transfer of membrane-bound antigens between cells can be mediated by a variety of mechanisms; for instance, it has been shown that B cells are able to acquire membrane-bound antigens at 4°C, in contrast to T cells [18].
Parameters governing biomechanics (elasticity and damping of cells) can be calibrated within biologically plausible bounds using results from cell rheology experiments [20].
The interaction between DCs and NK cells can be mediated through cell-cell contact, membrane-bound ligands, or by a variety of soluble factors, such cytokines and prostanoids that contribute to the modulation of the activity of both cell types.
The minute amount of vitamin B12 needed by cells can be provided by the receptor endocytosis of TC-bound B12 from blood (TC) [7], [8].
Even in the absence of elevated levels of serum IgE, cell-bound IgE can be detected on peripheral blood cells in a subgroup of patients.
The result indicates that although cell surface-bound Notch can be internalized in awd mutant cells in the presence of Rab5CA, it is not processed and cannot enter late endosomes.
The two cell surface-bound forms can be shed and thus three soluble forms of uPAR can be identified in the blood 11.
Cell cycle CDKs of differing phosphorylation status and in monomeric and cyclin-bound forms can be detected in cells, suggesting that such states are accessible for targeting.
Bound (3.1) can be verified as follows.
Overall, a similar common bound conformation can be assumed.
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