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The regulatory regions bound by FOS at genes differentially regulated during transformation highlight its importance to many STAT3-regulated processes such as G protein-coupled receptor signaling, NF-κB signaling, cellular movement, and cell death (not shown).
Lastly, many STAT3 binding sites are also bound by FOS and the expression of several AP-1 factors is altered during transformation in a STAT3-dependent manner, suggesting that STAT3 may cooperate with AP-1 proteins.
As this transformation may lead to locally very large slip values, we constrained its upper bound by the maximum of the original model.
We're bound by it.
And we are bound by them.
They are bound by certain treaties.
Private sales are bound by confidentiality agreements.
"Because we are bound by duty.
"I'm bound by a confidentiality agreement".
We are bound by the evidence".
Canada is not bound by those rules.
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Justyna Jupowicz-Kozak
CEO of Professional Science Editing for Scientists @ prosciediting.com