Sentence examples for bound and soluble forms from inspiring English sources
Future investigations on localization of membrane bound and soluble forms of RAGE, as well as RAGE induced biochemical pathways shall further identify the role of RAGE in the central nervous system.
The presence of Muc4 in goblet cells and enterocytes is similar to that described for human tissue, and is consistent with previously published work showing that MUC4 can be produced both in membrane bound and soluble forms [40], [41].
It differs from other chemokines not only in its structure and relatively large size, but also in the fact that it occurs in both membrane bound and soluble forms.
CXCL16 is a recently described CXC chemokine that is found in both membrane bound and soluble forms, the latter following cleavage by a disintegrin and metalloproteinase 10 (ADAM10) [ 41].
Cytokine receptors exist in membrane bound and soluble form.
The monoclonal antibody that we used in our study binds and neutralizes murine TNF-α; it was a surrogate for infliximab, a monoclonal antibody that binds the membrane-bound and soluble forms of human TNF-α and prevents their binding to cellular receptors [20].
Both the membrane-bound and soluble forms of RANKL attach to RANK, a receptor on the cell surface of osteoclast precursors, to stimulate osteoclastogenesis [ 5].
Membrane-bound and soluble forms of the single chain I-Ab stimulated an antigen-specific T cell hybridoma, and tetramers made from soluble monomers stained these cells.
BLyS is a type II protein produced in both membrane-bound and soluble forms by stromal cells, macrophages, dendritic cells and neutrophils [18].
The MS associated interleukin-7 receptor (IL-7R) gene [16] is suspected to be involved in MS etiology through the differential splicing of membrane-bound and soluble forms [17].
Other genes that regulate disease by differential splice-variant expression are IL2RA and IL7R, which may involve dysregulation of their membrane-bound and soluble forms in MS patients [12], [72], [73].
