N. meningitidis strain MC58 does not possess the Hb-Hp receptor, but produces TbpAB, for Tf uptake, LbpAB, for Lf uptake, and HmbR, which binds and removes haem from Hb [23] [26].
It has been shown that HSL, in order to effectively continue triglyceride degradation, interacts with aP2, which binds and removes fatty acids from lipid droplets [ 19].
Some patients may require hemodialysis to support kidney function, or a newer technique called liver dialysis which uses a dialysis circuit with albumin-bound membranes to bind and remove toxins normally cleared by the liver, providing a means of extracorporeal liver support until transplantation can be performed.
RHG family members in Drosophila contain the IAP-Binding-Motif (IBM) domain in their N-terminal, which binds to and removes the inhibitory activity of IAP [ 21, 28, 67] as well as their structural and functional homologs Smac/Diablo in mammals [ 68].
Heat shock proteins (encoded by genes hsp5, hsp13, hspb2, dnajb11, dnajb9, dnajc3), which bind, stabilise and remove damaged proteins, were also differentially regulated across various treatment groups.
Extensive resection is performed by Exo1 or DNA2-BLM in conjunction with Replication Protein A (RPA), which binds ssDNA and removes secondary structures (Sugiyama et al., 1998, Symington and Gautier, 2011).
For example, high molecular weight bioactive polymers can be restricted to gastrointestinal tract, where they can selectively recognize, bind, and remove target disease causing substances from the body.
For example, FACT (facilitates chromatin transcription), composed of the HMG-1-like protein, SSRP1 and p140/Spt16, transiently binds and removes H2A/H2B dimers from nucleosomes [7].
N. meningitidis is not believed to synthesize siderophores, but produces several surface receptors that are able to bind and remove the iron or haem from host iron binding proteins: Tf, Lf, Hb, and Hb-Hp complexes [18] [21].
The reduced detoxification capacity of albumin is especially important, as it suggests that the molecule cannot bind and remove waste products.
