A bottom-up methodology based on component level failure mode and effect analysis (FMEA) has been applied to perform the safety analyses for Chinese ITER TBM design with helium-cooled solid breeder (HCSB) concept for testing in ITER device.
This represents an especially interesting opportunity to reform our current diagnostic system using a bottom-up research methodology based on digital and biological markers data instead of the classical traditional top-down approach.
This represents an especially interesting opportunity to reform our diagnostic system using a bottom-up research methodology based on digital and biological markers data instead of the current top-down approach centred on our limited classification systems.
To overcome this problem a bottom-up methodology is proposed, which relies on the basic idea that the system configuration is certainly based on one or more thermodynamic cycles that may share some processes or be combined in a cascade form.
A bottom-up methodology was developed to determine marginal costs in existing facilities due to changes in the SWM system, based on the determination of average costs in such waste facilities as function of key facility and waste compositional parameters.
A concept for a structured bottom-up methodology is put forward that motivates, engages, enables and empowers all stake holders to identify, prioritize, and address safety challenges.
The aim of our research was to apply an in-depth proteomic bottom-up methodology to characterize the urinary proteome of ADPKD population in comparison to healthy controls.
In addition, a bottom-up methodology was used to estimate the cost of some of the resources used at individual patient level.
This paper presents a concept for structured bottom-up methodology that enables and empowers all stakeholders to identify, prioritize, and address safety challenges.
Even though the setting and the costing methodology used (a step-down allocation method using cost centres) were quite different from ours (bottom-up methodology), the results are surprisingly similar.
These principles can be found in other works based on the constructivist approach, artificial life, subsumption architecture and other bottom-up methodologies.
