In his locker-room address last Monday, the co-owner Wellington Mara reminded the players not to accept the "rock-bottom" description of their season after last Sunday's 20-13 loss in Dallas, and he asked for a renewed commitment to the final four games.
Single molecule detection characterizes individual states of a system providing the "bottom-up" description that can be uniquely formulated and tested without the ambiguities inherent in ensemble derived observations [1].
Atomistic models provide a bottom-up description of material properties and processes, and MD simulation is capable of solving the dynamic evolution of equilibrium and non-equilibrium processes.
We also give a bottom-up description of how temporal identities all arise from the notion of distinct events situated in time and the durations separating them.
In order to provide a bottom-up description of materials behavior from a fundamental perspective, here we apply an atomistic multi-scale simulation approach that considers the structure-process-property paradigm of materials science and the architecture of proteins from the atomistic level up to the overall structure.
As expected, the regions corresponding to the mature miRNA as well as the loop (see Figure 1 (bottom) for the description of the miRNA regions) displayed a lower occurrence of variants than the rest of the miR 5' and 3' regions.
Extensions of the approach of Hattis et al. (2002) can also be developed to construct "bottom up" quantitative descriptions of PK variability that can be applied as defaults across classes of chemicals.
Once Mr. Cameron has sent the Bismarck to the bottom (the computer-aided description of its slide down an undersea mountain is fascinating), the film loses some of its pulse and enters a wonkier phase.
Conversely, whoever wrote "It is not bulky either as it just extends a little at the bottom" in the product description ought to immediately undergo a workplace evaluation.
Decide will also alert you if you're unwittingly looking at an older iteration of a product you want, and at at the bottom of each product description, it presents a timeline of releases so that users can view when prior iterations were released and when it predicts new models to arrive.
You'll find these at the bottom of the app description page.
