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Here's what needs to be done: Funders should pay attention to the career bottlenecks that exist in different disciplines and tailor their investment accordingly.
The Medical and Related Sciences Discovery District (MaRS), which is rising on a muddy plot of land in the midst of Toronto's research and health sciences centre, "was created to address the bottlenecks that exist in the commercialisation process in Canada," thereby accelerating innovation, explains John Cook, president and chief operating officer of the nonprofit MaRS corporation.
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The bottleneck that exists in traditional security and cloud and modern applications, is in the investigation phase," Frampton said.
First, the Przewalski's horse population that existed prior to the bottleneck might have possessed substantial levels of genetic diversity and some of this diversity may have carried across.
Several data suggest that bottlenecks mainly exist at the post-transcriptional level, and most probably within the secretory pathway [ 4, 5].
Low genetic load may exist in some outcrossing species if they have recently passed through narrow genetic bottlenecks that have purged the most deleterious recessive alleles.
Why would that exist then?
Instead, it will create bottlenecks that do the opposite.
"Metal eliminates many performance bottlenecks that are found in traditional graphics APIs".
Clearly, the lack of a strong UPR response in some strains producing low levels of heterologous proteins strongly suggests that also non-UPR mediated bottlenecks exist in A. niger that hamper efficient secretion.
Many bottlenecks also exist for improving those physical and chemical properties.
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CEO of Professional Science Editing for Scientists @ prosciediting.com