Sentence examples for both wt and variant from inspiring English sources

These results indicate that both WT and variant GCases in mouse fibroblasts responded to diltiazem and verapamil.

One GKRP unit of both WT and variant P446L regulatory protein were subsequently used per equimolar activity assay.

Experiments using fixed concentrations of both WT and variant regulatory protein confirmed that there was no difference in F1P-mediated inhibition of the two GKRPs at concentrations up to and including 500 µ m of phosphate ester (92.5 ± 2.6% for WT versus 90.1 ± 1.8% for P446L; n = 9; P = 0.2), despite the initial difference in intrinsic inhibitory capacity at 0 µ m F1P (Fig.  2B).

Together, these results suggest a crucial role of W32 in maintaining the structure and stability of SOD1 in the context of both WT and G93A variants, consistent with our observation from the above TEM and DSF analysis.

Together these results indicated that (i) all viruses replicate similarly in cell culture, (ii) the WT and variant forms of the IFNα/βBPs are not required for infection in cell culture, and (iii) the IFNα/βBPGAGmut versions are correctly synthesised by the engineered viruses during infection.

The second theme of note is a tendency for alanine-rich sequences to undergo α-helical to β structure transitions [29], [30], suggesting that structural studies of ovine Sho protein with wt and variant (Ala 3Gly repeat arrays may prove fruitful.

Recombinant GST-tagged GCK and WT and variant FLAG-tagged GKRP proteins were prepared as described previously (9, 29).

We expressed and purified recombinant human GCK and wild-type (WT) and variant human GKRP to explore the effects of rare GCKR variants on the GCK GKRP interaction.

Binding kinetics of F1P and F6P to WT and variant FLAG-tagged GKRP were measured by MST in a NanoTemperMonolith NT.115 LabelFree instrument (NanoTemper Technologies).

Stable transfectants of human wild-type (WT) and variant SDHC cDNA were prepared in B9 cells, and the clones with similar level of SDHC were selected.

To better understand this phenomenon, we performed in silico molecular docking simulation of MitoVES and UbQ with the Qp site of WT and variant CII.