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The improved survival of P. falciparum in NSG was associated with an absence of significant production of the two major inflammatory cytokines IL-6 and IFNγ, whereas both were elevated in the NOD/SCID model [6].
Average cord mercury levels were more than twice maternal levels, and both were elevated in women who reported eating fish/seafood during pregnancy.
A previous study found a correlation between levels of melanin and ROS, showing that both were elevated in melanocytes from dysplastic nevi compared to those from normal skin of the same individual [ 6].
Both were elevated in the contralateral kidney of the db RAS mice in comparison to both WT RAS and db sham mice, indicating presence of inflammation that was not apparent in either the WT RAS or the db sham.
We also noted connected clusters of metabolites related to glycolysis (fructose, glucose-6-phosphate, fructose-6-phosphate) and glycogenolysis (malto-triose, malto-tetraose, malto-pentose), both were elevated in ER- cancers.
Stage-specific transcriptomic studies in B. malayi confirmed the presence of ALT-1 and ALT-2 in both larval stages examined (L3 and L4), however, transcript [ 38] and protein [ 47] levels of both were elevated in the L3 stage.
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In addition to IL-6, STAT3 is activated by IL-10, and circulating levels of both are elevated in AP patients [ 11], thus possibly contributing to the constitutive pSTAT3 expression.
MMP-9 is important for the budding of endothelial cells, and TIMP-1 is an inhibitor of MMP-9; both are elevated in serum and synovial tissues of patients with RA.
The authors found that, depending on the type of tumor, the levels of two ligands of ActRIIB – myostatin or activin (or both) – are elevated in tumor-bearing mice, and that administration of sActRIIB brings them back to normal levels.
Both expressions were elevated in HCC patient samples.
Both subclasses were elevated in RA extracts compared with those in OA.
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