In this study, allele frequency (in 88 of 90 genetic variants) and genotype prevalence (in 87 of 90 variants) differed significantly by race/ethnic group.
In contrast, the recovery of the NIBSC, but not the calibrator IL-6 variants, differed significantly in terms of their sensitivity to matrix types, regardless of assay type.
However, after 60 min, cell surface expression of the truncated hIPΔ312 and hIPΔ307 variants differed significantly from the hIP with evidence of altered trafficking or recycling, i.e., they exhibited altered time-dependent movement to and from the cell surface followed by further internalization, and after 4 h incubation both hIPΔ312 and hIPΔ307 were located at the cell surface.
As mentioned above, both TLR4 and TIRAP/Mal genetic variants differ significantly in their frequency according to geographic locations [ 14, 15].
Even though all genetically engineered collagen variants differ significantly from the wild-type collagen II, most of them were able to form filamentous structures.
It should also be evident that the absolute runtime (on these platforms and with our current Spark implementation) of the deterministic and non-deterministic variants differ significantly such that the naïve implementation can be approximately 20 times faster (in the contexts of both platforms).
These splice variants differ significantly in their ability to (i) bind F-actin, (ii) cross-link F-actin (iii) activate Arp2/3 mediated actin polymerization and (iv) induce cell migration in vitro [ 14].
The encoded enzyme variants differ significantly in the ethanol concentrations they require for maximal function and in how fast they metabolize the ethanol (i.e., in their kinetic properties), with both ADH1B*2 and ADH1B*3 encoding enzymes with faster turnover (i.e., higher Vmax) than the reference allele (see table 1).
They conclude that the presence of rs1695 variant differed significantly between responders and non-responders.
But neither the FOX2 gene expression nor expression of any transcript variant differed significantly between NSCLC and NAT.
