Sentence examples for both types of variants from inspiring English sources
Both types of variants were up-regulated in the frontal cortex and striatum of HD patients.
We developed a unified framework for the joint association testing of both types of variants.
Hence, determining both types of variants is a prerequisite to further correlate genetic architecture and phenotype [ 4].
For our simulations, we considered three phenotype models: "Rare" (only rare variants or haplotypes are risk-contributing), "Common" (only common variants or haplotypes), and "Both" (both types of variants or haplotypes).
If it is the case that both common and rare variants contribute to ADHD risk, but genome-wide significant association cannot be a realistic goal with currently sized samples, we might expect to see a convergence of subthreshold signals from both types of variants influencing common biological risk pathways.
They found that SNPs and CNVs captured 83.6% and 17.7% of the total detected genetic variation in gene expression, respectively, but the signals from the two types of variation had little overlap, suggesting interrogation of the genome for both types of variants may be an effective way to elucidate the variation in complex phenotypes and human diseases (Stranger, Forrest et al. 2007).
This implies that both types of gene variants are relevant to ADHD risk.
Interestingly, the relative amounts of both types of miR-101 varinnthein the brain differed according to age.
Both types of pseudoword variants elicited enhanced negativity in a later time window of the N400 pseudoword effect.
Furthermore, a significant difference between both types of pseudoword variants [t(15) = 12.21, p <.01] but not between both types of words [t(15) = 0.23, n.s.] relates this early ERP deflection to mismatch detection in the case of coronal pseudowords.
The presence of both types of miR-101 varinnts in Ago2 immunocomplexes was confirmed in publicly available high-throughput sequencing data of endogenous Ago2-associated sRNAs in HEK293T and mouse NIH-3T3 cells (GEO datasets GSM337571 and GSM849857 respectively).
