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Exact(20)
We obtained DNA oligomer frequencies at SNPs and DIMs and in their corresponding reference regions to address whether both types of mutations were subject to similar mutational hotspots.
Both types of mutations may co-exist, and if located on the same allele (α0), produce a reproductive risk of hydrops fetalis.
The rates of both types of mutations could be selected for.
Both types of mutations occur frequently in HIV, particularly in poorly conserved regions, such as HIV gag.
Both G C and A∶T mutations were detected, suggesting that the lesion introduced by AID is sufficient for triggering both types of mutations.
If selection has no effect on fitness, both types of mutations are fixed at the same rate and dN/dS = 1, while in the case of positive selection, non-synonymous substitutions are fixed at a rate exceeding that of synonymous (or silent) substitutions, and the ratio dN/dS is larger than 1.
Similar(40)
Both types of mutation prevented nicking by RepD.
This suggests that both types of mutation would render the subclones resistant to 6-TG selection.
We then combined both types of mutation to generate AcNgn3KO, which contains no canonical sites of ubiquitylation.
This is because differences in population size will modulate the efficacy of selection against both types of mutation.
For HS vs non-HS comparisons, if a sample contained both types of mutation, it was excluded from the analysis.
More suggestions(17)
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