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Decreased kidney function and kidney damage may predate hypertension, but only a few studies have investigated both types of markers simultaneously, and these studies have obtained conflicting results.
Although the AFLP dataset provided higher resolution than the SSR dataset, both types of markers provided comparable and unbiased results.
Taken together, our qualitative and quantitative analysis of CRISPR- and VNTR-based genotyping methods revealed that both types of markers are characterized by significant amounts of homoplasy.
Issues with allelic dropout will apply to both types of markers although the specific problem of 'short allele dominance' is only relevant to microsatellites.
Bayesian clusters, principal coordinate analysis and population genetic distance trees all classified the oaks into two main groups consistent with the morphological differentiation of the two taxa rather than with geographic locations using both types of markers.
Both types of markers are known to be sensitive to changes in the reaction conditions and hence to frequently miscall genotypes, while in tests the SNP genotyping assay employed here consistently assigned the majority of species-specific genotypes correctly when studying pure strain individuals of N. vitripennis and N. giraulti (J. D. Gibson, unpubl. results).
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Both types of marker layers show a good visibility without any parasitic influences on the crystal structure or growth behavior.
Our analyses from R. leschenaulti using both types of marker revealed little evidence of genetic structure across the study region.
To assess the effectiveness and accuracy of each kind of marker we compared maps built with each marker type separately and with both types of marker combined.
Guidelines for mapping studies that employ microsatellites and SNPs simultaneously are provided, as we recognise that sometimes it is practical to combine datasets containing both types of marker.
In particular, we show that when combining both types of marker the conventional process of building linkage maps, whereby the most informative markers are added to the map first, has to be modified in order to improve map accuracy.
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