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These observations are extended to show the stimulation of oxidative metabolism by DCA increases collagen I production; in contrast DCA inhibits collagen I production by normoxic adhesion fibroblasts as well as under hypoxic conditions in both types of fibroblasts.
CSCC7 cells in direct co-culture enhanced and activated MMP-2 in the medium of both types of fibroblasts.
In both types of fibroblasts Sant 7 completely blocked IL-6+IL-6sR stimulatiof of aromatase activity.
We detected α4 and β1 integrins on the surface of both types of fibroblasts, an integrin pair known to bind thrombospondin-1 [ 49].
In replicate co-cultures of MCF10A cells with three different NAF and CAF grown in an E F of 2 1, both types of fibroblasts significantly reduced proliferation of MCF10A cells.
Although MBD3, the suppression of which can increase reprogramming efficiency [ 97], was highly expressed in both hOFs and hDFs, these results suggested that both types of fibroblasts might have a similar advantage of reprogramming both cell fate and plasticity.
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Although thrombin receptor was expressed on both types of synovial fibroblasts, its level was significantly higher in RA than OA fibroblasts (Fig. 1b).
It was found that cell viability for both types of cells, fibroblast proliferation, and HUVEC attachment were the highest at a 0.5 wt.% GO loading whereas oxygen plasma treatment also enhanced HUVEC viability and attachment significantly.
JAM-C is expressed on synovial and other types of fibroblasts, fibroblastic reticular cells of lymph nodes, and smooth muscle cells [ 10, 23].
Tumor necrosis factor (TNF) triggering can induce both types of PCD in fibroblasts, that is, apoptotic and necrotic.
As was discussed above, both types of cells, macrophages and fibroblasts, are involved in a intricate liaison with tumor cells, that usually leads to tumor progression and activation of the metastatic cascade.
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